Recent insights from Dectin-1-Pattern Recognition Receptor

Abstract

Abstract: The Dectin-1 is a non-Toll-like pattern recognition receptor expressed predominantly by myeloid cells, which can induce its own intracellular signalling and can mediate a variety of cellular responses, plays a key role in anti-fungal immunity. The recent studies have focused on the signalling pathways from Dectin-1, interactions between Dectin-1 and other PRRs, Dectin-1 and adaptive immunity and the role of Dectin-1 in anti-microbial immunity.

Key words: Dectin-1, signalling pathways, adaptive immunity, anti-microbial immunity

CLC Number:

R392.1

YI Xiu-li, LIU Bin, QI Xiao-long. Recent insights from Dectin-1-Pattern Recognition Receptor[J]. Chinese Journal of Mycology, 2012, (2): 121-124.

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