Abstract: Objective To evaluate clinical efficacy and safety of sertaconazole nitrate cream in the treatment of children's skin candidiasis(moniliasis).Methods One hundred patients were enrolled in the test and were divided into 2 groups. Sertaconazole nitrate cream was applied topically to the affected areas of the body twice daily for 14 days in the treatment group.Miconazole nitrate ointment was applied topically to the affected areas of the body twice daily for 14 days in the control group.The efficacy and the adverse reaction were observed.Result Treatment group's curative rate is 92.00% and control group's 64.00%(P<0.01).Compared with the control group, the treatment group produced the effect more quickly with a shorter cured period(P<0.01).There was little adverse effect observed in the test.Conclusion Sertaconazole nitrate cream acts effectively and safely on children's skin candidiasis. It is worthy of application.

Key words: sertaconazole nitrate cream, candidiasis, children