Abstract: Objective To investigate the risk factors and prevention methods of deep fungal infection after general surgery.Methods The clinical and mycological materials of 48 cases with deep fungal infection after general surgery from 2006 to 2009 were retrospectively analyzed.Results Fifty-six strains were isolated from different specimens of the 48 patients.Candida albicans was the most frequently isolated pathogen,which accounted for 41.1%.Long-term and combination usage of broad-spectrum antibiotic,and underline disease were the risks factor for fungal infection.Conclusions The deep fungal infection is not uncommon and a severe complication after general surgery.Candida albicans was still the most frequently isolated pathogen.Appropriate use of antibiotics,timely mycological test and early diagnosis and treat in time were important for fungal infection.

Key words: deep fungal infection, Candida albicans, general surgery