小型无绿藻致血流感染1例及文献复习

摘要/Abstract

摘要： 患者,男,44岁,农民。全身皮肤散在红色斑疹、左小腿皮肤溃烂伴发热。在皮肤伤口分泌物及血液中均培养出酵母样菌落,菌落涂片显示不同大小的球形孢子囊,具有桑葚样外观。最终确诊为无绿藻菌感染,予以氟康唑、伊曲康唑治疗后死亡。本病例包含的数据及其文献复习将增加医务工作者对该病原体的认识。

关键词: 小型无绿藻菌, 血流感染, 皮肤感染

Abstract: A 44-year-old male farmer presented with erythematous plaques of the whole body, diffusely infiltrated erosions on his left leg and fever. Smooth, creamy-white, yeast-like colonies grew from skin biopsy specimen and blood specimen after 72 h of incubation. Electron microscopy demonstrated 'morula' or daisy-like appearance of its endosporulating sporangia. These findings were consistent with a diagnosis of protothecosis. The patient was treated with fluconazole and itraconazole but finally died. This case and the literature review will increase the knowledge of this pathogen.

Key words: Prototheca wickerhamii, bloodstream infection, cutaneous protothecosis

中图分类号:

R 519.5

张旭, 李晨, 潘娟, 李足意, 聂格. 小型无绿藻致血流感染1例及文献复习[J]. 中国真菌学杂志, 2023, 18(3): 246-249,253.

ZHANG Xu, LI Chen, PAN Juan, LI Zuyi, NIE Ge. Bloodstream infection caused by Prototheca wickerhamii:a case report and review of the literatures[J]. Chinese Journal of Mycology, 2023, 18(3): 246-249,253.

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