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中国真菌学杂志 2023, Vol. 18  Issue (2): 151-155.

病例报告 上一篇    下一篇

肺普通裂褶菌感染并肺不张1例并文献复习

叶景焕1, 陈珠妮1, 刘玉2, 李亚清2, 谢纬2   

  1. 1. 广州中医药大学第四临床医学院, 518033 深圳;
    2. 深圳市中医院呼吸与危重症医学科, 518033 深圳
  • 收稿日期:2022-02-21 出版日期:2023-04-28 发布日期:2023-05-26
  • 通讯作者: 谢纬,E-mail:xiew0703@163.com E-mail:xiew0703@163.com
  • 作者简介:叶景焕,男(汉族),硕士研究生在读.E-mail:13265025021@163.com
  • 基金资助:
    国家自然科学基金(81904103);深圳市"医疗卫生三名工程"项目(SZSM201812063)

Pulmonary infection caused by Schizophyllum commune complicated with atelectasis: a case report and review of the literature

YE Jinghuan1, CHEN Zhuni1, LIU Yu2, LI Yaqing2, XIE Wei2   

  1. 1. Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen 518033, China;
    2. Shenzhen Hospital of Traditional Chinese Medicine, Shenzhen 518033, China
  • Received:2022-02-21 Online:2023-04-28 Published:2023-05-26

摘要: 普通裂褶菌(Schizophyllum commune, S. commune)是一种丝状真菌,为条件致病菌,引起人深部侵袭性感染国内报道罕见。我院收治了1例免疫功能正常患者肺部感染S. commune,广东人,既往体健,临床表现为反复出现的非刺激性咳嗽、咳黄白色黏液痰,胸部CT示右肺上叶肺不张并黏液栓,纤支镜下可见右肺上叶黏液栓堵塞及大量黄色脓性分泌物,肺泡灌洗液培养出S. commune,给予伊曲康唑抗真菌治疗1周后症状好转出院,出院后继续服用伊曲康唑3个月,随访复查胸部CT示病灶吸收,右肺上叶完全复张,提示抗真菌治疗有效。

关键词: 普通裂褶菌, 肺部感染, 肺不张, 纤支镜, 伊曲康唑

Abstract: Filamentous fungus Schizophyllum commune(S. commune) is a conditional pathogen. There were rare reports of S. commune caused deep invasive infection in human. A patient with pulmonary infection of S.commune with normal immune function was treated in our hospital, who came from Guangdong and presented recurrent non-irritating cough and yellowish-white mucus sputum. Computed tomography of the patient’s chest showed atelectasis with mucus thrombus in the upper lobe of the right lung. Fiberoptic bronchoscopy revealed that there was a mucinous embolus in the upper lobe of the right lung with massive yellow purulent discharge. Alveolar lavage fluid culture were positive for S. commune. His clinical status was improved and discharged after a week of itraconazole treatment. After being discharged from the hospital, the patient was maintained on itraconazole treatment for 3 months,computed tomography of the patient’s chest showed that the lesion was absorbed and the upper lobe of the right lung was completely dilated at his final follow-up, which suggested that the antifungal treatment was effective.

Key words: Schizophyllum commune, pulmonary infection, atelectasis, fiberoptic bronchoscopy, itraconazole

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