[1] YOUNIS N,ZARIF R, MAHFOUZ R. Inflammatory bowel disease:between genetics and microbiota[J].Mol Biol Rep,2020,47(4):3053-3063. [2] 岳宏宇,丛春莉,李艳梅.肠道微生态与肠道疾病关系的研究进展[J].中国真菌学杂志,2020,15(4):240-243. [3] NISHIDA A,INOUE R,INATOMI O,et al. Gut microbiota in the pathogenesis of inflammatory bowel disease[J].Clin J Gastroenterol,2018,11(1):1-10. [4] RAMOS G P,PAPADAKIS K A. Mechanisms of disease:inflammatory bowel diseases[J].Mayo Clin Proc,2019,94(1):155-165. [5] ZHANG Y Z,LI Y Y. Inflammatory bowel disease:pathogenesis[J].World J Gastroenterol,2014,20(1):91-99. [6] SOKOL H,LEDUCQ V,ASCHARD H,et al. Fungal microbiota dysbiosis in IBD[J].Gut,2017,66(6):1039-1048. [7] NISHINO K,NISHIDA A,INOUE R,et al. Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease[J].J Gastroenterol,2018,53(1):95-106. [8] OTT S J,KVHBACHER T,MUSFELDT M,et al. Fungi and inflammatory bowel diseases:alterations of composition and diversity[J].Scand J Gastroenterol,2008,43(7):831-841. [9] 王承党.关注炎症性肠病患者的真菌感染问题[J].胃肠病学,2017,22(11):641-646. [10] 潘丽雅,阮冰.炎症性肠病患者的肠道真菌改变及其致病机制探讨[J].临床内科杂志,2021,38(4):220-222. [11] IMAI T,INOUE R,KAWADA Y,et al. Characterization of fungal dysbiosis in Japanese patients with inflammatory bowel disease[J].J Gastroenterol,2019,54(2):149-159. [12] QIU X,ZHANG F,YANG X,et al. Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis[J].Sci Rep,2015,5(1):10416. [13] 沈鑫,姚羽菲,李继遥,等.人体真菌组与疾病[J].华西口腔医学杂志,2019,37(3):314-319. [14] 孙耀华,白辰光.念珠菌与消化道肿瘤关系的相关研究进展[J].中国真菌学杂志,2021,16(2):137-140. [15] HONNEFFER J B,MINAMOTO Y,SUCHODOLSKI J S. Microbiota alterations in acute and chronic gastrointestinal inflammation of cats and dogs[J].World J Gastroenterol,2014,20(44):16489-16497. [16] KÖHLER J R,HUBE B,PUCCIA R,et al. Fungi that infect humans[J].Microbiol Spectr,2017,5(3):10. [17] PELEG A Y,HOGAN D A,MYLONAKIS E. Medically important bacterial-fungal interactions[J].Nat Rev Microbiol,2010,8(5):340-349. [18] AUCHTUNG T A,FOFANOVA T Y,STEWART C J,et al. Investigating colonization of the healthy adult gastrointestinal tract by fungi[J].mSphere,2018,3(2):e00092-18. [19] KAPITAN M,NIEMIEC M J,STEIMLE A,et al. Fungi as part of the microbiota and interactions with intestinal bacteria[J].Curr Top Microbiol Immunol,2019,422:265-301.DOI:10.1007/82_2018_117. [20] BERNARDES E,PETTERSEN V K,GUTIERREZ M W,et al. Intestinal fungi are causally implicated in microbiome assembly and immune development in mice[J].Nat Commun,2020,11(1):2577. [21] MATSUOK,HAKU A,BI B,et al. Fecal microbiota transplantation prevents Candida albicans from colonizing the gastrointestinal tract[J].Microbiol Immunol,2019,63(5):155-163. [22] SOVRAN B,PLANCHAIS J,JEGOU S,et al. Enterobacteriaceae are essential for the modulation of colitis severity by fungi[J]. Microbiome,2018,16(1):152. [23] BEHESHTI-MAAL A,SHAHROKH S,ANSARI S,et al. Gut mycobiome:the probable determinative role of fungi in IBD patients[J].Mycoses,2021,64(5):468-476. [24] PELLON A, NASAB S,MOYES D L. New insights in Candida albicans innate immunity at the mucosa:toxins,epithelium,metabolism,and beyond[J].Front Cell Infect Microbiol,2020,10:81. DOI:10.3389/fcimb.2020.00081. [25] 车媛,刘凯,李秋荣.真菌菌群在肠道疾病中的作用进展[J].肠外与肠内营养,2015,22(6):378-381. [26] GARCIA-RUBIO R,Oliveira H C,Rivera J,et al. The fungal cell wall:Cryptococcus, and Aspergillus species[J].Front Microbiol,2020,10:2993. DOI:10.3389/fmicb.2019.02993. [27] THOMPSON A,DAVIES L C,LIAO C T,et al. The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors[J].PLoS Pathog,2019,15(6):e1007850. [28] 张浩楠,周学东,徐欣,等.口腔微生物与炎症性肠病的关系[J].华西口腔医学杂志,2019,37(4):443-449. [29] 牛海静,苏秉忠.消化道真菌及其相关疾病研究进展[J].中国真菌学杂志,2015,10(6):377-379,384. [30] POULAIN D.Candida albicans,plasticity and pathogenesis[J]. Crit Rev Microbiol,2015,41(2):208-217. [31] LIGUORI G,LAMAS B,RICHARD M L,et al. Fungal dysbiosis in mucosa-associated microbiota of Crohn's disease patients[J]. J Crohns Colitis,2016,10(3):296-305. [32] LIMON J J,TANG J,LI D,et al. Malassezia is associated with Crohn's disease and exacerbates colitis in mouse models[J].Cell Host Microbe,2019,25(3):377-388. [33] LEE S C. mSphere of influence:the mycobiota in human health and disease[J].mSphere,2020,5(1):e00974-19. [34] LEONARDI I,LI X,SEMON A,et al. CX3CR1+ mononuclear phagocytes control immunity to intestinal fungi[J].Science,2018,359(6372):232-236. [35] SHAO T Y,ANG W,JIANG T T,et al. Commensal Candida albicans positively calibrates systemic Th17 immunological responses[J].Cell Host Microbe,2019,25(3):404-417. [36] BACHER P,HOHNSTEIN T,BEERBAUM E,et al. Human anti-fungal Th17 immunity and pathology rely on cross-reactivity against Candida albicans[J].Cell,2019,176(6):1340-1355.e15. [37] 葛晓龙,曹裕,王婷婷.肠道内Th17细胞的特征及其在炎症性肠病中的作用[J].免疫学杂志,2014,30(12):1113-1117. [38] 楼伟,王伟东,曹生辉.芍药汤加减辅助西药治疗溃疡性结肠炎对患者YKL-40、IL-17的变化研究[J].中华中医药学刊,2022,40(1):3. [39] DARYA A,NICOLAS L. Generation and expansion of T helper 17 lymphocytes ex vivo[J].Methods Mol Biol,2016,1371:101. DOI:10.1007/978-1-4939-3139-2_7. [40] KUMAMOTO C A. Inflammation and gastrointestinal Candida colonization[J].Curr Opin Microbiol,2011,14(4):386-91. [41] ILIEV I D,CADWELL K. Effects of intestinal fungi and viruses on immune responses and inflammatory bowel diseases[J].Gastroenterology,2021,160(4):1050-1066. [42] WHEELER M L,LIMON J J,BAR A S,et al. Immunological consequences of intestinal fungal dysbiosis[J].Cell Host Microbe,2016,19(6):865-873. [43] DAWSON T L.Malassezia:The forbidden kingdom opens[J].Cell Host Microbe,2019,25(3):345-347. [44] SPATZ M,RICHARD M L. Overview of the potential role of Malassezia in gut health and disease[J].Front Cell Infect Microbiol,2020,10:201. DOI:10.3389/fcimb.2020.00201. [45] LAM S,ZUO T,HO M,et al. Review article:fungal alterations in inflammatory bowel diseases[J].Aliment Pharmacol Ther,2019,50(11-12):1159-1171. [46] MATIJAŠIć M,MEŠTROVIć T,PALJETAK H,et al. Gut microbiota beyond bacteria-mycobiome,virome,archaeome,and eukaryotic parasites in IBD[J].Int J Mol Sci,2020,21(8):2668. [47] WOLF A J,LIMON J J,NGUYEN C,et al. Malassezia spp. induce inflammatory cytokines and activate NLRP3 inflammasomes in phagocytes[J].J Leukoc Biol,2021,109(1):161-172. [48] WRIGHTON K H. Malassezia restricta plays CARDs in the gut[J].Nat Rev Microbiol,2019,17(5):266-267. [49] DRUMMOND R A,FRANCO L M,LIONAKIS M S. Human CARD9:a critical molecule of fungal immune surveillance[J].Front Immunol,2018,9:1836. DOI:10.3389/fimmu.2018.01836. [50] MA J,ABRAM C L,HU Y,et al. CARD9 mediates dendritic cell-induced development of Lyn deficiency-associated autoimmune and inflammatory diseases[J].Sci Signal,2019,12(602):eaao3829. [51] WANG T,FAN C,YAO A,et al. The adaptor protein CARD9 protects against colon cancer by restricting mycobiota-mediated expansion of myeloid-derived suppressor cells[J].Immunity,2018,49(3):504-514. [52] MALIK A,SHARMA D,MALIREDDI R K S,et al. SYK-CARD9 signaling axis promotes gut fungi-mediated inflammasome activation to restrict colitis and colon cancer[J].Immunity,2018,49(3):515-530. [53] 田雨,王化虹.血清学检测ASCA和ANCA在炎症性肠病诊治中的应用价值[J].中华检验医学杂志,2018,41(10):708-711. [54] JAWHARA S,POULAIN D. Saccharomyces boulardii decreases inflammation and intestinal colonization by Candida albicans in a mouse model of chemically-induced colitis[J].Med Mycol,2007,45(8):691-700. [55] GANJI-ARJENAKI M,RAFIEIAN-KOPAEI M. Probiotics are a good choice in remission of inflammatory bowel diseases:a meta analysis and systematic review[J].J Cell Physiol,2018,233(3):2091-2103. [56] 庄鑫.布拉氏酵母菌对溃疡性结肠炎患者血清炎性因子及肠道菌群的影响[J].中国临床药理学杂志,2020,36(10):1198-1201. [57] 尹娟,庞智.消化道真菌在克罗恩病中的研究进展[J].胃肠病学,2019,24(10):614-618. [58] 王瑰娜,赵蕴卿,毛志芹. sIgA在炎症性肠病小鼠肠黏膜中的表达及布拉酵母菌的干预作用[J].中国微生态学杂志,2015,27(10):1131-1135. [59] ZHOU H,ZHANG H J,Guan L,et al. Mechanism and therapeutic effects of Saccharomyces boulardii on experimental colitis in mice[J]. Mol Med Rep,2018,18(6):5652-5662. |