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中国真菌学杂志 2018, Vol. 13  Issue (3): 181-183.

病例报告 上一篇    下一篇

近平滑念珠菌性肉芽肿1例

闻轶旸1, 陈裕充2, 蔡晴1, 杨连娟1   

  1. 1. 上海市皮肤病医院真菌病科, 上海 200050;
    2. 上海市皮肤病医院皮肤外科, 上海 200050
  • 收稿日期:2017-12-04 出版日期:2018-06-28 发布日期:2018-06-28
  • 通讯作者: 杨连娟,E-mail:lianjuan_yang@aliyun.com E-mail:lianjuan_yang@aliyun.com
  • 作者简介:闻轶旸,男(汉族),硕士研究生,住院医师.E-mail:13774341912@163.com
  • 基金资助:

    上海市卫计委面上项目(20140388)

Monilial granuloma caused by Candida parapsilosisis: a case report

WEN Yi-yang1, CHEN Yu-chong2, CAI Qing1, YANG Lian-juan1   

  1. 1. Department of Mycoses, Shanghai Dermatology Hospital, Shanghai 200050, China;
    2. Department of Dermatosurgery, Shanghai Dermatology Hospital, Shanghai 200050, China
  • Received:2017-12-04 Online:2018-06-28 Published:2018-06-28

摘要:

报道1例面颈部近平滑念珠菌性肉芽肿。患者男,15岁,面颈部发疹2个月余,查体:右面部、颈部共3处直径1~3 cm大小环状暗红斑块,边缘隆起,中央坏死结痂,表面少许渗液。颈部皮损组织病理见表皮假上皮瘤样增生,真皮内弥漫性致密炎细胞浸润,以淋巴细胞及组织细胞为主,伴较多嗜酸性粒细胞、浆细胞;局部坏死,血管增生扩张。组织块真菌培养示近平滑念珠菌。诊断:近平滑念珠菌性肉芽肿。治疗:伊曲康唑胶囊100 mg/次,2次/d口服,联苯苄唑乳膏外用6周,同时皮肤镜观察疗效,症状明显改善。目前仍在治疗随访中。

关键词: 肉芽肿, 念珠菌, 近平滑念珠菌, 皮肤镜

Abstract:

A case of monilial granuloma caused by Candida parapsilosisis was reported. A-15-year-old boy had a history of rash on the face and neck for 2 months. Physical examination showed 3 annular plaques with diameters of 1-3 cm on his right face and neck. The margin of the lesions was edematous and swollen, and the centre was necrotic and crusted. There was a slight yellow exudation on the surface. A biopsy of neck lesion revealed pseudoepitheliomatous hyperplasia of epidermis, diffuse inflammatory cell infiltration into the dermis, mainly in lymphocytes, eosinophils, and plasma cells, with local necrosis and vascular proliferation. The isolate from the biopsy specimen was identified as Candida parapsilosisis. The patient was discharged on oral itraconazole 100 mg twice daily and external bifonazole cream for 6 week, while using dermoscopy to evaluate the efficacy of treatment, the lesions were slightly improved. The patient is still under treatment.

Key words: granuloma, Candida, Candida parapsilosisis, dermoscopy

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