关键词: 足癣, 复发, 硝酸硫康唑喷雾剂, 鞋袜喷药

Abstract:

Objective To evaluate the efficacy and safety of sulconazole nitrate spray 1% in the treatment of tinea pedis and to observe the effect of spraying the socks and shoes on preventing the disease from recurrence. Methods One hundren and twenty patients diagnosed as tinea pedis were randomly divided into two groups, being treated with sulconazole nitrate spray 1% and miconazole nitrate cream 2% respectively.The clinical efficacy was evaluated after two weeks and four weeks. 30 clinically cured patients would continue to spray their shoes and socks to control the local environmental fungi for one month. Then the recurrence rate was compared with that of the other 30 patients without any further treatment. Results Clinical efficiency of experimental and control groups were 90.48% and 49.23% respectively after 4 weeks. There was no significant difference between the two groups (P=0.085). The recurrence rates of the group who had continued to spray the socks and shoes and the group who had not continued to use drugs were respectively 10% and 26.7%.The difference was statistically significant (P=0.038). Conclusion This study suggested that sulconazole nitrate spray 1% was effective and safe in the treatment of tinea pedis. Spraying the socks and shoes with sulconazole nitrate spray 1% would reduce the recurrence of tinea pedis.

Key words: tinea pedis, recurrence, sulconazole nitrate spray, spray the socks and shoes