JUC长效抗菌材料治疗体股癣和手足癣144例的疗效观察

摘要/Abstract

摘要：

目的观察JUC长效抗菌材料治疗体股癣和手足癣的疗效。方法选取体股癣32例，足癣78例，手癣34例，将JUC长效抗菌材料喷洒患处和周围所有皮肤，3次/d，疗程4周；同时喷洒患者的鞋、袜、毛巾、衣裤等，1次/d，3个月后进行复发评定。结果 4周后，临床总有效率为95.83%，真菌学有效率为72.92%。体股癣、足癣和手癣的有效率分别为93.75%、96.15%和97.06%。对138例痊愈患者随访3个月，复发3例，复发率为3.13%。结论 JUC长效抗菌材料治疗体股癣和手足癣疗效满意，不良反应少，复发率低。

关键词: JUC长效抗菌材料, 体癣, 股癣, 手癣, 足癣

Abstract:

Objective To observe the treatment effect of JUC long-acting antimicrobial material on tinea corporis,manus and pedis.Methods Thirty-two tinea corporis and cruris,78 tinea pedis and 34 tinea manus were enrolled in the study.All participants were treated with JUC long-acting antimicrobial material spray,three times per day and the treatment lasted for 4 weeks.Meanwhile,all participants' shoes,socks and towels and clothes were also sprayed with JUC long-acting antimicrobial material,one time per day.Results At the end of treatment,the total clinical cure rate was 95.83%(138 of 144) and the mycology clearance was 72.92%(105 0f 144).The cure rates of tinea corporis and cruris,tinea pedis and tinea manus were 93.75%,96.15% and 97.06% separately.After three months of treatment,recurrence rate was 3.13%(3 of 138).Conclusions Treating tinea corporis and cruris,tinea pedis and tinea manus with JUC long-acting antimicrobial material is safe,effective and able to decrease the recurrence.

Key words: JUC long-acting antimicrobial material, tinea corporis, tinea cruris, tinea manus, tinea pedis

中图分类号:

韦士才. JUC长效抗菌材料治疗体股癣和手足癣144例的疗效观察[J]. 中国真菌学杂志, 2016, 11(4): 232-234,239.

WEI Shi-cai. A clinical study on JUC long-acting antimicrobial material for tinea corporis and cruris, manus and pedis treatment[J]. Chinese Journal of Mycology, 2016, 11(4): 232-234,239.

参考文献

[1] Dias MF,Quaresma-Santos MV,Bernardes-Filho F,et al.Update on therapy for superficial mycoses:review article part I[J].An Bras Dermatol,2013,88(5):764-774.
[2] Pereiro Ferreiros MJr,Garcia-Martinez FJ,Alonso-Gonzalez J.Update on the treatment of superficial mycoses[J].Actas Dermosifiliogr,2012,103(9):778-783.
[3] 中国中西医结合学会皮肤性病专业委员会,中华医学会皮肤性病学分会真菌学组.手癣和足癣的诊疗指南[J].中国真菌学杂志,2012,7(2):109.
[4] Deva R,Shankaranarayanan P,Ciccoli R,et al.Candida albicans induces selectively transcriptional activation of cyclooxygenase-2 in HeLa cells:pivotal roles of Toll-like receptors,p38 mitogen-activated protein kinase,and NF-kappa B[J].J Immunol,2003,171(7):3047-3055.
[5] Gupta AK,Skinner AR,Cooper EA.Evaluation of the efficacy of ciclopirox 0.77% gel in the treatment of tinea pedis interdigitalis(dermatophytosis complex) in a randomized,double-blind,placebo-controlled trial[J].Int J Dermatol,2005,44(3):590-593.
[6] Gupta AK,Chow M,Daniel CR,et al.Treatments of tinea pedis[J].Dermatol Clin,2003,21(期次):431-462.
[7] 中华人民共和国卫生部药政局.《新药(西药)临床研究指导原则汇编》[S].北京:人民卫生出版社,1993.
[8] 张雅洁,李青.口服特比萘芬联合外用联苯苄唑乳膏治疗足癣长期临床研究[J].中国真菌学杂志,2011,6(4):220-224.
[9] 王爱平,杨海珍,万喆,等.2%硝酸舍他康唑乳膏治疗体股癣和足癣疗效和安全性评价[J].中国真菌学杂志,2006,1(5):291-295.
[10] Zeng Y,Deng R,Yeung B,et al.Application of an antibacterial dressing spray in the prevention of post-operative infection in oral cancer patients:A phase 1 clinical trial[J].African Journal of Biotechnology,2008,7(21):3827-3831.
[11] Ng M,Wong C,Chan Y.Comparsion between JUC spray and silver sulphadiazine cream dressing in the management of second degree burn wounds in an accident and emergency department in HongKong[J],Hong Kong J Emerg Med,2009,10,16(4):285-286.
[12] Wan K,Ng M,Wong Y.New horizon on community-acquired methicillin resistant Staphylococcus aureus(CA-MRSA) skin and soft tissue infection:nanotechnology antimicrobial spray[J].Hong Kong J Emerg Med,2011,18(6):432-436.
[13] He W,Ye Z,Wang D.Application a anotechnology antimicrobial spray to prevent lower urinary tract infection:a multi urology centers trial[J].Journal of Translational Medicine,2012,10(1):S14.
[14] Tam B,Chow S.A preliminary report on the effectiveness of Nanotechnology Anti-Microbial Spray Dressing in preventing tenckhoff Catheter Exit-Site Infection[J].Peritoneal Dialysis International,2014,34(6):670-673.
[15] Li W,Ma X,Peng Y,et al.Application of a nano-antimicrobial film to prevent ventilator-associated pneumonia:A pilot study[J].African Journal of Biotechnology,2011,10(10):1926-1931.
[16] Yuen J,Yung J.Medical implications of antimicrobial coating polymers-organosilicon quaternary ammonium chloride[J].Mod Chem Appl,2013,1(3):3
[17] 郭俊岗,龚长根,辛勇,等.综合疗法治疗念珠菌性包皮龟头炎36例疗效观察[J].临床皮肤科杂志,2000,29(4):251.
[18] 魏跃钢,闵仲生,陈垒,等."皮肤物理抗菌膜"专利技术治疗足癣的疗效观察[J].皮肤病与性病,2010,6,32(2):31-32.
[19] 王磊.口服特比萘芬联合外用丙烯胺类药物治疗复发性足癣疗效观察[J].中国社区医师(医学专业),2010,12(227):66.
[20] Al Hasan M,Fitzgerald SM,Saoudian M,et al.Dermatology for the practicing allergist:Tinea pedis and its complications[J].Clin Mol Allergy,2004,2(1):5-16.
[21] 陈传俊,于益鹏,孙步梅,等."皮肤物理抗菌膜"与常用抗生素对临床耐药菌株药敏情况的比较研究[J].皮肤病与性病,2011,6,33(3):129-131.