血液细菌感染对血清(1,3)-β-D-葡聚糖检测结果的影响

中国真菌学杂志　 2016, Vol. 11 　Issue (1): 24-27.

血液细菌感染对血清(1,3)-β-D-葡聚糖检测结果的影响

王明达¹, 陈若虹², 黄佳斯¹, 李晶¹, 王玲², 李慧², 刘茵茵², 杜文涵², 申婷², 吕星²

1. 长沙市第三医院检验科, 长沙 410000;
2. 中南大学湘雅二医院检验科, 长沙 410000

收稿日期:2015-09-08 出版日期:2016-02-28 发布日期:2016-02-28
通讯作者: 吕星,E-mail:feibo6@126.com E-mail:feibo6@126.com
作者简介:王明达,男(汉族),本科,主任技师.E-mail:251037792@qq.com

The effect of blood bacterial infection on the serum(1,3)-β-D-beta result

WANG Ming-da¹, CHEN Ruo-hong², HUANG Jia-si¹, LI Jing¹, WANG Ling², LI Hui², LIU Yin-yin², DU Wen-han², SHEN Ting², LV Xing²

1. Department of Clinical Laboratory, The Third Hospital of Changsha, Changsha 410000, China;
2. Department of Clinical Laboratory, The Second Xiangya Hospital of Central South University, Changsha 410000, China

Received:2015-09-08 Online:2016-02-28 Published:2016-02-28

摘要/Abstract

摘要：

目的探讨血液细菌感染对血清(1,3)-β-D-葡聚糖检测结果的影响。方法排除影响G试验结果的干扰因素后,选取符合入组条件的血培养细菌阳性及血培养阴性患者各40例,采集血清进行G试验检测。结果40例血培养细菌阳性标本中革兰阳性菌22例,革兰阴性菌18例,其中只有1例大肠埃希菌的G试验结果为阳性,4例在灰区,其余为阴性。40例血培养阴性标本3例G试验结果在灰区,其余为阴性。血培养细菌阳性组与血培养阴性组G试验结果差异无统计学意义(P>0.05)。结论血液细菌感染对G试验检测干扰较小。

关键词: (1,3)-β-D-葡聚糖, 菌血症, 交叉反应

Abstract:

Objective To evaluate the influences of bacterial infections on the(1,3)-β-D-glucan detection.Method Serums of forty patients with identification of positive blood culture and forty patients with identification of negative blood culture,after controlling disturbance,were detected by G tests.Results Among 22 patients with Gram positive bactereamia and 18 patients with Gram negative bactereamia,only one patient identified as Escherichia coli infection was positive for G test,while four patients were G test suspicious and the rest were negative.Among 40 patients with negative blood culture,three patients were known as G test suspicious while the rest were negative.There is no statistic significance of G test results between specimens with blood culture positive and negative(P>0.05).Conclusion Bacterial infections have minor influences on G test detection in this study.

Key words: (1,3)-β-D-glucan, bacteraemia, cross reactivity

中图分类号:

R446.5

王明达, 陈若虹, 黄佳斯, 李晶, 王玲, 李慧, 刘茵茵, 杜文涵, 申婷, 吕星. 血液细菌感染对血清(1,3)-β-D-葡聚糖检测结果的影响[J]. 中国真菌学杂志, 2016, 11(1): 24-27.

WANG Ming-da, CHEN Ruo-hong, HUANG Jia-si, LI Jing, WANG Ling, LI Hui, LIU Yin-yin, DU Wen-han, SHEN Ting, LV Xing. The effect of blood bacterial infection on the serum(1,3)-β-D-beta result[J]. Chinese Journal of Mycology, 2016, 11(1): 24-27.

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