关键词: 甲真菌病, 临床分型, 病原菌, 流行病学

Abstract:

Objective To study the clinical classification and pathogenic fungi and to analyze the related factors with regard to the patients of onychomacosis in the Fourth Hospital of Hebei Medical University.Methods The patients were from dermatology outpatient within the period from January to December in 2011. In each case, the most serious nail was selected as target nail and the method of multiple point fungal culture was adopted. The fungal culture examination was positive and diagnosis was onychomycosis. The strains were identified to species. Onychomycosis-related factors were logged into the questionnaire.Results The clinical classification of all the 106 cases of onychomycosis were DLSO 47.17%, TDO 45.28%, PSO 4.95%, and SWO 2.97%. There were 111 fungal stains including dermatophytes 72 (64.86%), yeast 34 (30.63%), and NDM (nondermatophyte moulds, NDM)5 (4.50%). The patient's age (year) and duration (month) showed positive correlation: the older the age, the longer the duration. The number of infected nails and duration were positive correlation, that is, longer duration, more numbers. The most common nail changes were discoloration (84.91%) and thickening (74.53%). Single nail infection was found in 101 cases, accounting for 95.28%; mixed fungal infection was found in 5 cases that there were two kinds of fungi existing together in one patient, one of them was dermatophytes, and the other was yeast.Conclusion Onychomycosis was a chronic progression disease. The clinical classification of onychomycosis was complex and the pathogenic funguses were multiple. So the disease shall be paid much attention and given early treatment.

Key words: onychomycosis, clinical classification, pathogens, epidemiology