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中国真菌学杂志 2012, Vol.  Issue (5): 290-292,311.

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生殖器念珠菌病家庭内感染的临床研究

李艳, 乌日娜   

  1. 内蒙古医科大学附属医院皮肤科, 呼和浩特 010010
  • 收稿日期:2012-07-06 出版日期:2012-10-28 发布日期:2012-10-28
  • 作者简介:李艳,女(汉族),硕士,主治医师.E-mail:ly100606@sina.com
  • 基金资助:
    内蒙古医学院青年基金项目(NY2006QN008)

Investigation on genital candidias within couples

LI Yan, WU Ri-Na   

  1. Department of dermatology, Affiliated Hospital of Inner Mongolia Medical University, Huhehaote 010010
  • Received:2012-07-06 Online:2012-10-28 Published:2012-10-28

摘要: 目的 了解引起夫妻双方生殖器念珠菌病的病原菌是否为同一种致病菌,并行药物敏感性检测,以指导临床治疗。方法 采用常规念珠菌培养方法培养, API 20C AUX进行鉴定,微量稀释法行药敏检测。结果 88例患者 (44对夫妻)中,检出白念珠菌73例。夫妻双方共同由同一菌种致病例数为41对,白念珠菌引起者为36对,光滑念珠菌引起者为2对,近平滑2对,克柔念珠菌1对。与对照组相比,差异有统计学意义。体外药敏显示88株念珠菌对制霉菌素全部敏感,对克霉唑也高度敏感,对伊曲康唑、氟康唑有不同程度的耐药。结论 夫妻一方患有生殖器念珠菌病时,另一方应做好性伴通知工作,行相应检查,必要时行药敏实验,以降低念珠菌病的复发率。

关键词: 生殖器念珠菌病, 阴道念珠菌病, 性传播, 药敏实验

Abstract: Objective To investigate wether the genital candidiasis is resulted from the same pathogenic fungus between the couple and to guide the clinic treatment by drug sensitivity test.Methods Use common ways to cultivate candida. API 20C AUX and the microdilution method were used to do identification and drug sensitivity test of candida.Results Eighty-eight genital candida strains were isolated. Fouty-one couples surffered from the same candida, which was significant diffrence compared with the control (P<0.05) Eighty-eight genital candida strains were senstive to nystatin and clotrimazole,but showed different drug resistence with itraconazole and fluconazole.Conclusion When one of the couple suffer from genital candidias, the other should have detail examination and individual therapy in order to reduce the rate of recurrence.

Key words: genital candidias, vulvoaginal candidias, sexual transmission, drug senitive test

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