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中国真菌学杂志 2011, Vol. 6  Issue (6): 361-362.

病例报告 上一篇    下一篇

多变根毛霉致面部皮肤毛霉病1例

周村建, 王莉, 徐艳, 钟白玉, 郝飞   

  1. 第三军医大学西南医院皮肤性病科, 重庆, 400038
  • 收稿日期:2011-03-28 出版日期:2011-12-28 发布日期:2011-12-28
  • 通讯作者: 郝飞,E-mail:haofei62@medmail.com.cn E-mail:haofei62@medmail.com.cn
  • 作者简介:周村建,男(汉族),博士,副教授.E-mail:zhoucj@sins.com

A case of primary cutaneous mucormycosis caused by Rhizomucor variabilis

ZHOU Cun-jian, WANG Li, XU Yan, ZHONG Bai-yu, HAO Fei   

  1. Department of Dermatology and Venereology, Southwest Hospital, Third Military Medical University, Chongqing, 400038
  • Received:2011-03-28 Online:2011-12-28 Published:2011-12-28

摘要: 报道1例由多变根毛霉引起的面部皮肤毛霉病。患者男,65岁,面部结节斑块伴痒半年余。皮损组织病理检查示真皮中下层有炎细胞及多核巨细胞浸润,并见粗大较短的无隔菌丝。经真菌培养和分子生物学鉴定,菌种鉴定为多变根毛霉。皮损经短时两性霉素B治疗后好转。

关键词: 皮肤毛霉病, 多变根毛霉, 两性霉素B

Abstract: A 65-year-old man with diffused swelling plaques in the face for half a year was reported.Characteristic broad,non-septate hyphae were found in the lesion by histopathology.The isolate was identified as Rhizomucor variabilis by fungal culture,PCR and sequence analysis.The patient was diagnosied as primary cutaneous mucormycosis and improved after systemic amphotericin B for 12 days,with total dosage of 1 050 mg.

Key words: cutaneous mucormycosis, Rhizomucor variabili, amphotericin B

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