真菌球型真菌性鼻窦炎及其骨炎临床特征

中国真菌学杂志　 2023, Vol. 18 　Issue (4): 315-319.

真菌球型真菌性鼻窦炎及其骨炎临床特征

钟丽¹, 王永鑫¹, 李新华², 刘继英², 肖仪¹

1. 福建医科大学附属南平第一医院耳鼻咽喉头颈外科, 南平 353000;
2. 福建医科大学附属南平第一医院病理科, 南平 353000

收稿日期:2022-05-20 出版日期:2023-08-28 发布日期:2023-09-02
通讯作者: 肖仪,E-mail:190929728@qq.com E-mail:190929728@qq.com
作者简介:钟丽,女(畲族),硕士,主治医师.E-mail:553980492@qq.com
基金资助:
福建省自然科学基金面上项目(卫生联合资助)(2020J01122297)

Clinical characteristics of fungal ball sinusitis and it’s osteitis

ZHONG Li¹, WANG Yongxin¹, LI Xinhua², LIU Jiying², XIAO Yi¹

1. Department of Otolaryngology-Head and Neck Surgery, Nanping 353000, China;
2. Department of Pathology;Affiliated the First Hospital of Nanping of Fujian Medical University, Nanping 353000, China

Received:2022-05-20 Online:2023-08-28 Published:2023-09-02

摘要/Abstract

摘要： 目的研究真菌球型真菌性鼻窦炎(FBS)及其骨炎临床特征。方法回顾性分析105例(共110窦)FBS患者的临床资料,总结分析其症状、体征、影像学特点、病理特点以及骨炎的临床特征。结果 110窦中97窦(88.2%)位于上颌窦,13窦(11.8%)位于蝶窦;97窦(88.2%)较对侧(即健侧)鼻窦存在骨质不同程度增厚。病变鼻窦及对侧鼻窦窦壁骨质在厚度(0.34±0.17 vs. 0.14±0.08)、CT值(1161.5±322.5 vs. 864.2±482.8)、骨炎GOSS评分(3.0±1.4 vs. 0.3±0.9)三个方面均存在明显统计学差异。病理学观察病变鼻窦骨质存在明显骨髓炎的表现并伴有骨质重塑活动。结论真菌球型真菌性鼻窦炎好发于上颌窦和蝶窦,单窦为主。大部分病变鼻窦窦壁骨质存在明显的骨炎,主要表现为骨质增厚以及CT值增高。

关键词: 真菌球, 真菌性鼻窦炎, 骨炎

Abstract: Objective The aim of this study is to the clinical features of fungal spheroid fungal sinusitis and osteitis. Methods The clinical data of 105 FBS patients (110 sinuses in total) were retrospectively analyzed,the clinical features of their symptoms, signs, image, pathology, and osteitis were summarized and analyzed. Results Among the 110 sinuses, 97 sinuses (88.2%) were located in the maxillary sinus, and 13 sinuses (11.8%) were located in the sphenoid sinus; 97 sinuses (88.2%) had different degrees of bone thickening compared with the contralateral sinus. The wall bone of lesion sinus and contralateral sinus were significantly different in bone thickness (0.34±0.17 vs. 0.14±0.08), CT value (1161.5±322.5 vs. 864.2±482.8), GOSS score (3.0±1.4 vs. 0.3±0.9) .Pathological observation showed manifestations of osteomyelitis accompanied by bone remodeling activities. Conclusion Fungal spheroid fungal sinusitis prefer to occurs in the maxillary sinus and sphenoid sinus, mainly in single sinus. Most of the wall bone around the lesion sinuses have obvious osteitis, which is mainly characterized by bone thickening and increased CT value.

Key words: fungal ball, fungal sinusitis, osteitis

中图分类号:

R765.4 R519

钟丽, 王永鑫, 李新华, 刘继英, 肖仪. 真菌球型真菌性鼻窦炎及其骨炎临床特征[J]. 中国真菌学杂志, 2023, 18(4): 315-319.

ZHONG Li, WANG Yongxin, LI Xinhua, LIU Jiying, XIAO Yi. Clinical characteristics of fungal ball sinusitis and it’s osteitis[J]. Chinese Journal of Mycology, 2023, 18(4): 315-319.

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