关键词: 尖端赛多孢子菌, 肺部感染, 中枢神经系统感染, 脑脓肿, 治疗措施

Abstract: To reported one case of pulmonary infection and encephalopyosis caused by Scedosporium apiospermum, and to discuss the clinical features and the treatment. The patient’s broncholveolr lvge fluid, cerebrospinal fluid and intracranial drainage specimens were taken for fungal culture and morphological identification, and next generation sequencing. Surgical drainage and voriconazole antifungal therapy were used. According to the morphological characteristics of the strain and the results of gene sequencing, it was identified as Scedosporium apiospermum. Pulmonary and central nervous system fungal infections caused by Scedosporium apiospermum are less common and their identification relies primarily on morphological features and genetic analysis. Surgical drainage and voriconazole have a good therapeutic effect on this. However, a further follow-up is requied.

Key words: Scedosporium apiospermum, pulmonary infection, central nervous system infections, encephalopyosis, treatment therapy