快速现场评价技术在肺隐球菌病诊断中的应用价值

摘要/Abstract

摘要： 目的探索快速现场评价技术(rapid on site evaluation, ROSE)在经皮肺穿刺活检诊断肺隐球菌病的准确性和时效性。方法回顾性分析25例经穿刺活检病理、组织培养、外科手术病理确诊为肺隐球菌的病例资料,包括患者影像学特征、ROSE、病理诊断,各诊断耗费时间以及诊断费用。结果以最终诊断为标准,ROSE准确率、敏感性、特异性分别为80%、80%、100%,ROSE、病理报告出具平均时间分别为(10±1) min、(81±1.4) h;诊断费用分别为220元、450元。结论与最终诊断相比较,ROSE对诊断肺隐球菌病具有较好准确性及时效性,并且可以节省经济成本,值得在呼吸介入诊断中应用及推广。

关键词: 肺隐球菌病, 快速现场评价, 组织病理学, 经皮肺穿刺

Abstract: Objective To explore the accuracy and timeliness of rapid on-site evaluation site (ROSE) in the diagnosis of pulmonary cryptococcosis by percutaneous lung biopsy. Methods A retrospective analysis of 25 cases of percutaneous lung biopsy pathologically diagnosed as pulmonary cryptococcus, including patient imaging, ROSE and pathological diagnosis results, time-consuming, and diagnosis costs was performed. Results Based on the final diagnosis, and the accuracy, sensitivity, and specificity of ROSE were 80%, 80%, and 100%, respectively. The average time for the issuance of ROSE and pathology reports were (10±1) min and (81±1.4) h, respectively; the diagnosis cost were 220 and 450 yuan, respectively. Conclusion ROSE had high accuracy and timeliness in the diagnosis of Cryptococcus neoformans pneumonia, and economic cost savings. It is worthy of application and promotion in the diagnosis of cryptococcus neoformans pneumonia in respiratory intervention.

Key words: pulmonary cryptococcosis, rapid on-site evaluation, histopathology, percutaneous lung puncture

中图分类号:

R519.4

王汉生, 成丹, 任涛, 尤辉, 魏娜, 罗国仕, 王梅芳. 快速现场评价技术在肺隐球菌病诊断中的应用价值[J]. 中国真菌学杂志, 2023, 18(1): 33-37,57.

WANG Hansheng, CHEN Dan, REN Tao, YOU Hui, WEI Na, LUO Guoshi, WANG Meifang. Clinical value of rapid on site evaluation in the diagnosis of pulmonary cryptococcosis[J]. Chinese Journal of Mycology, 2023, 18(1): 33-37,57.

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