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中国真菌学杂志 2022, Vol. 17  Issue (3): 225-226.

病例报告 上一篇    下一篇

Fonsecaea monophora所致着色芽生菌病1例

刘瑞真, 陈静, 徐明, 卢万丁   

  1. 福州市皮肤病防治院, 福州 360000
  • 收稿日期:2020-03-26 出版日期:2022-06-28 发布日期:2022-07-02
  • 通讯作者: 卢万丁,E-mail:lwdfuzhou@163.com E-mail:lwdfuzhou@163.com
  • 作者简介:刘瑞真,女(汉族),硕士,主治医师.E-mail:992556551@qq.com

A case of cutaneous chromoblastomycosis caused by Fonsecaea monophora

LIU Ruizhen, CHEN Jing, XU Ming, LU Wanding   

  1. Dermatology Hospital of Fuzhou, Fuzhou 36000, China
  • Received:2020-03-26 Online:2022-06-28 Published:2022-07-02

摘要: 患者,男,63岁,因“左手腕结节斑块半个月”为主诉就诊我科门诊。左手腕肥厚性的肉色斑块,结节,表面疣状增生,病理活检见真皮及多核巨细胞胞浆内褐色厚壁圆形硬壳小体。PAS染色(+),真菌培养见暗棕至黑色菌落生长;经测序,最终确诊为Fonsecaea monophora所致着色芽生菌病。予口服伊曲康唑治疗,但由于患者原发矽肺症状加重,后因矽肺引发并发症死亡。

关键词: 着色芽生菌病, Fonsecaea monophora, 伊曲康唑

Abstract: A 63-year-old male presented with a nodule on the left wrist for half a month. Physical examination showed hyperkeratotic plaques and nodule on the left wrist. Histopathological examination revealed a number of brown and roundish thick-walled sclerotic bodies in dermis and multinucleated giant cells. PAS staining was positive. Fungus culture test observed dark-brown to dark fungi which was confirmed as Fonsecaea monophora by sequencing. The patient was treated with oral itraconazole, but finally died of complications of silicosis.

Key words: chromoblastomycosis, Fonsecaea monophora, itraconazole

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