侵袭性真菌感染分子病理诊断进展

摘要/Abstract

摘要： 组织病理学是诊断侵袭性真菌感染的金标准之一，但由于病原真菌在组织学中形态的相似性以及混合感染的存在，难以将病原真菌鉴定到属或种水平。分子病理诊断方法如聚合酶链式反应（PCR）、基于激光捕获显微切割的LCM-PCR及荧光原位杂交（FISH）对福尔马林固定石蜡包埋（FFPE）组织中病原真菌具有高效、快速、高特异性的诊断价值。该文主要针对分子病理技术在侵袭性真菌感染领域的研究进展进行综述。

关键词: 侵袭性真菌感染, 激光捕获显微切割, 聚合酶链式反应, 荧光原位杂交

中图分类号:

R446.5

刘晓, 李若瑜, 宋营改. 侵袭性真菌感染分子病理诊断进展[J]. 中国真菌学杂志, 2021, 16(2): 141-144.

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