难治性孢子丝菌病1例

中国真菌学杂志　 2021, Vol. 16 　Issue (1): 48-50.

难治性孢子丝菌病1例

董嘉琤, 梁官钊, 徐秀莲, 刘维达

中国医学科学院北京协和医学院皮肤病研究所, 南京 210042

收稿日期:2019-12-13 发布日期:2021-02-25
通讯作者: 刘维达,E-mail:liumyco@hotmail.com E-mail:liumyco@hotmail.com
作者简介:董嘉琤,女(汉族),博士研究生在读.E-mail:dongjc2016@163.com

A case of refractory sporotrichosis

DONG Jiazheng, LIANG Guanzhao, XU Xiulian, LIU Weida

Chinese Academy of Medical Science and Peking Union Medical College, Institute of Dermatology, Nanjing 210042, China

Received:2019-12-13 Published:2021-02-25

摘要/Abstract

摘要： 报道1例因非医嘱习惯性口服激素导致的难愈性孢子丝菌病。患者右腕木屑刺伤后，出现局限性红斑伴破溃，曾多次外院就诊，诊断为"孢子丝菌病"，给予抗真菌治疗半年后病情仍不断恶化，遂来我院就诊。皮损经真菌镜检、培养及分子生物学测序均鉴定为孢子丝菌病，病理示感染性肉芽肿。询问病史时发现患者有日常口服激素的习惯，嘱患者停用激素并口服伊曲康唑4个月后治愈。

关键词: 孢子丝菌病, 激素, 免疫抑制, 治疗

Abstract: We report a case of refractory sporotrichosis due to the abuse of oral glucocorticoid. A 61-year-old female patient had a stab wound on the right wrist and was diagnosed as sporotrichosis. After antifungal treatment for six months, her condition deteriorated and came to our hospital for treatment. Fungal microscopy, culture, molecular biology detection and the pathological examination were performed and the results support the diagnosis of sporotrichosis. When asking about the medical history, it was found that the patient had the habit of taking oral glucocorticoid tablets on a daily basis. The patient was instructed to stop the glucocorticoid and take oral itraconazole for 4 months and was successfully cured eventually.

Key words: sporotrichosis, oral glucocorticoid, treatment

中图分类号:

R756.6

董嘉琤, 梁官钊, 徐秀莲, 刘维达. 难治性孢子丝菌病1例[J]. 中国真菌学杂志, 2021, 16(1): 48-50.

DONG Jiazheng, LIANG Guanzhao, XU Xiulian, LIU Weida. A case of refractory sporotrichosis[J]. Chinese Journal of Mycology, 2021, 16(1): 48-50.

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