关于重症新型冠状病毒肺炎继发侵袭性真菌感染实验室诊治建议

中国真菌学杂志　 2020, Vol. 15 　Issue (1): 1-5.

抗击新冠病毒感染专题下一篇

关于重症新型冠状病毒肺炎继发侵袭性真菌感染实验室诊治建议

余进, 刘伟, 陈伟, 张晓梅, 万喆, 王爱平, 李若瑜

北京大学第一医院皮肤性病科, 国家皮肤与免疫疾病临床医学研究中心, 北京大学真菌和真菌病研究中心, 皮肤病分子诊断北京市重点实验室, 北京 100034

收稿日期:2020-02-10 出版日期:2020-02-28 发布日期:2020-02-28
通讯作者: 李若瑜,E-mail:mycolab@126.com E-mail:mycolab@126.com
作者简介:余进,女(汉族),博士,主任医师.E-mail:yujin676@126.com
基金资助:
“十三五”科技重大专项“艾滋病和病毒性肝炎等重大传染病防治”课题（编号：2018ZX10712001）

Experts opinion on the laboratory diagnosis and treatment of invasive fungal infection secondary to severe novel coronavirus pneumonia

YU Jin, LIU Wei, CHEN Wei, ZHANG Xiao-mei, WAN Zhe, WANG Ai-ping, LI Ruo-yu

Department of Dermatology and Venerology, Peking University First Hospital;National Clinical Research Center for Skin and Immune Diseases;Research Center for Medical Mycology, Peking University;Beijing Key Laboratory of Molecular Diagnosis of Dermatoses, Peking University First Hospital, Beijing 100034, China

Received:2020-02-10 Online:2020-02-28 Published:2020-02-28

摘要/Abstract

摘要：

新型冠状病毒肺炎传染性强，发病率高，重症患者病死率高。重症新冠肺炎患者具备侵袭性真菌感染发生的高危因素，且已有重症病例出现继发或合并真菌感染报告。对重症新冠肺炎患者应积极进行侵袭性真菌感染相关的微生物学、血清学及分子生物学检查，及时发现合并或继发真菌感染，开展针对性抗真菌治疗，降低患者病死率。

关键词: 新型冠状病毒肺炎, 侵袭性, 真菌感染, 实验室诊断, 治疗

Abstract:

The morbidity rate and transmissibility of the novel coronavirus of zoonotic origin (COVID-19) infected pneumonia are high, and the fatality rate among severe cases is high. Severe cases have risk factors of invasive fungal infections (IFIs), with some of them being reported to have developed combined or secondary fungal infections. To minimize the fatality rate among severe cases, IFIs-related microbiological, serologic and molecular biology examinations should be aggressively applied for the early discovery of invasive fungal infections and the early usage of target antifungal agents.

Key words: novel coronavirus pneumonia, invasive, fungal infection, laboratory diagnosis, treatment

中图分类号:

R519

余进, 刘伟, 陈伟, 张晓梅, 万喆, 王爱平, 李若瑜. 关于重症新型冠状病毒肺炎继发侵袭性真菌感染实验室诊治建议[J]. 中国真菌学杂志, 2020, 15(1): 1-5.

YU Jin, LIU Wei, CHEN Wei, ZHANG Xiao-mei, WAN Zhe, WANG Ai-ping, LI Ruo-yu. Experts opinion on the laboratory diagnosis and treatment of invasive fungal infection secondary to severe novel coronavirus pneumonia[J]. Chinese Journal of Mycology, 2020, 15(1): 1-5.

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关于重症新型冠状病毒肺炎继发侵袭性真菌感染实验室诊治建议

Experts opinion on the laboratory diagnosis and treatment of invasive fungal infection secondary to severe novel coronavirus pneumonia

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