中国大陆地区赛多孢霉感染流行现状的回顾性分析

摘要/Abstract

摘要：

为了解中国大陆地区赛多孢霉感染流行情况及诊治现状，该文通过对1978年来中国大陆地区报道的赛多孢霉感染病例进行回顾性分析。发现我国临床赛多孢霉感染的致病菌种以尖端赛多孢霉为主。感染常见部位依次为眼、肺、颅内、鼻窦、皮肤、关节、脊柱。感染类型以创伤后局部感染为主，其他类型为溺水后感染、免疫功能明显受损后感染及呼吸道内定植感染等。目前我国病原学诊断主要依赖真菌培养，分子生物学方法应用较少。治疗以单独抗真菌药物治疗为主，体外药敏实验及既往诊治经验表明赛多孢霉对伏立康唑敏感度高。我国多数赛多孢霉感染预后良好，而多育赛多孢霉所致播散感染预后差。目前赛多孢霉感染早期诊断困难，应该提高对该病特点的认识、形态学诊断水平，并积极开展分子鉴定，以达到早期准确诊断、治疗。

关键词: 赛多孢霉感染, 赛多孢霉, Lomentospora, 诊断, 治疗

中图分类号:

R519.8

杨之辉, 余进, 李若瑜. 中国大陆地区赛多孢霉感染流行现状的回顾性分析[J]. 中国真菌学杂志, 2019, 14(3): 183-188,192.

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