ORPs家族在真核生物中的功能

摘要/Abstract

摘要：

氧化固醇结合蛋白OSBP （oxysterol binding protein）是一类存在于细胞质内，与氧化固醇具有高度亲和力的受体蛋白。与OSBP结构具有较高同源性的蛋白被称为OSBP相关蛋白-ORPs （oxysterol bindingprotein-related proteins）。OSBP以及ORPs组成蛋白家族-ORPs家族。ORPs家族广泛存在于真核生物，主要有三方面功能：细胞脂质代谢、囊泡运输及细胞信号传导。虽然已经发现ORPs家族在真核生物中具有多种功能，但目前研究主要集中于人和酵母，对ORPs家族在其他真菌中的研究相对较少。

关键词: ORPs家族, 真核生物, 功能, 真菌

中图分类号:

Q74
R379

张聪良, 杨静, 乔祖莎, 张谨宇, 冯文莉, 马彦. ORPs家族在真核生物中的功能[J]. 中国真菌学杂志, 2019, 14(1): 61-64.

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