关键词: 红色毛癣菌, Majocchi肉芽肿, 伊曲康唑

Abstract:

A clinically misdiagnosed metastatic tumor case, definitely diagnosed as granuloma caused by Trichophyton rubrum through histopathology, Mycological examination,molecular biological analysis, was reported. A 65-year-old woman presented with erythema, papules and nodules on the right forearm for three months. Physical examination showed erythema, papules and small nodules, some of which merged into annular plaque. Biopsy of one small nodule was done and histopathology demonstrated granuloma involving the follicle in the dermis, with spores and hyphae inside. Tissue culture and molecular biological test turned out to be Trichophyton rubrum. The final diagnosis was Majocchi granuloma caused by Trichophyton rubrum. The patient was treated with oral itraconazole, 0.2 g bid for five weeks and 0.2 g qd for 7 weeks, with a complete resolution,negative of mycology and no relapse during a half-year following.

Key words: Trichophyton rubrum, Majocchi granuloma, itraconazole