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中国真菌学杂志 2018, Vol. 13  Issue (2): 114-119.

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外用抗真菌药物治疗甲真菌病进展

王若珺, 李若瑜, 王爱平   

  1. 北京大学第一医院皮肤性病科 北京大学真菌和真菌病研究中心 皮肤病分子诊断北京市重点实验室, 北京 100034
  • 收稿日期:2017-04-30 出版日期:2018-04-28 发布日期:2018-04-28
  • 通讯作者: 王爱平,E-mail:wangap516@163.com E-mail:wangap516@163.com
  • 作者简介:王若珺,女(白族),博士研究生在读.E-mail:wangrj@bjmu.edu.cn
  • 基金资助:

    北京市自然科学基金(7164255)

Progess of topical antifungal agents for the treatment of onychomycosis

WANG Ruo-jun, LI Ruo-yu, WANG Ai-ping   

  1. Department of Dermatology & Venereology, Peking University First Hospital;Research Center for Medical Mycology, Peking University;Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing 100034, China
  • Received:2017-04-30 Online:2018-04-28 Published:2018-04-28

摘要:

本文就外用抗真菌药物治疗甲真菌病进展进行综述,包括在临床上已广泛应用的8%环吡酮甲涂剂及5%阿莫罗芬搽剂,美国FDA批准的两个新药10%艾氟康唑溶液及5%Tavaborole溶液,以及一些尚在研究中的卢立康唑、他扎罗汀等,并简述外用抗真菌药物治疗甲真菌病新剂型的应用。

关键词: 甲真菌病, 10%艾氟康唑溶液, 5%Tavaborole溶液, 外用

Abstract:

In this article, we reviewed topical antifungal agents for the treatment of onychomycosis at present, including the widely used agents, 8% ciclopirox nail lacquer and 5% amorolfine nail lacquer, and the agents recently approved by the FDA, 10% efinaconazole and 5% tavaborole solution, as well as luliconazole and tazarotene which being still in studies. The use of new formulations of topical antifungal drugs were also included in this review.

Key words: onychomycosis, efinaconazole, tavaborole, topical

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