关键词: 隐球菌脑膜炎, 结核性脑膜炎, 脑脊液, 误诊

Abstract:

To report one case of cryptococcal meningitis misdiagnosed as tuberculous meningitis.The patient was a 49-year-old female with intermittent headache,low fever,progressive visual and hearing damage for more than three months,who was diagnosed as tuberculous meningitis.After anti-tuberculous treatment for more than a month,the patient developed an elevated temperature to 39.4 degree,a severe headache and vomiting for 3 days.And the fungus cultivation of cerebrospinal fluid gotten by lumbar puncture was positive.Beside,the cryptococcal antigens titer testing was 1:80.So the patient was diagnosed as cryptococcal meningitis.Nowdays the condition of the patient was better than before and the etiological examinations of the cerebrospinal fluid become negative after antifungal treatments for half a year.

Key words: cryptococcal meningitis, tuberculous meningitis, cerebrospinal fluid, misdiagnosed