1960~2015年湖北及周边地区头癣病原菌变化情况分析

中国真菌学杂志　 2017, Vol. 12 　Issue (2): 98-101,105.

1960~2015年湖北及周边地区头癣病原菌变化情况分析

毛叶红, 何蒙文, 郑岳臣, 连昕, 曾敬思

华中科技大学同济医学院附属协和医院皮肤性病科, 武汉 430022

收稿日期:2016-11-01 出版日期:2017-04-28 发布日期:2017-04-28
通讯作者: 曾敬思,E-mail:wuhanzjs@aliyun.com E-mail:wuhanzjs@aliyun.com
作者简介:毛叶红,女(汉族),本科,主管检验师.E-mail:49231918@qq.com;何蒙文,女(壮族),硕士研究生在读.E-mail:hmw5369@126.com

Causative agents of tinea capitis isolated from the patients in Hubei province and surrounding area in China during 1960-2015

MAO Ye-hong, HE Meng-wen, ZHENG Yue-chen, LIAN Xin, ZENG Jing-si

Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

Received:2016-11-01 Online:2017-04-28 Published:2017-04-28

摘要/Abstract

摘要：

目的了解1960~2015年间湖北及周边地区头癣病例的病原菌变化情况。方法归类、统计1960~2015年间我院皮肤性病科真菌室分离、鉴定来自头癣病例的病原真菌种类和数量。鉴定方法包括形态学、生理及生化实验方法。结果本地区20世纪60年代头癣高发，病原菌以许兰毛癣菌（41.9%）和紫色毛癣菌（31.0%）为主。70年代病例数锐减。90年代，犬小孢子菌比例达高峰（36.9%）后下降，目前罕见。近5 a紫色毛癣菌已取代许兰毛癣菌，成为本地区主要病原菌（63.0%）。许兰毛癣菌、红色毛癣菌多见于成人，而紫色毛癣菌、犬小孢子菌、趾（指）间毛癣菌和铁锈色小孢子菌均更多见于儿童。成年患者中女性所占比例（64.6%）显著高于儿童患者中女性比例（50.6%）（除许兰毛癣菌外）（P<0.05）。结论本地区头癣病原菌种类不断变迁，目前优势菌为紫色毛癣菌。

关键词: 头癣, 许兰毛癣菌, 紫色毛癣菌, 犬小孢子菌, 趾(指)间毛癣菌

Abstract:

Objective To understand the pathogens of tinea capitis during the period 1960-2015.Methods Fungal strains isolated from the patients with tinea capitis in the Medical Mycology Clinical Laboratory were subjected to a classification and statistical analysis.Morphological, physiological and biochemical methods were applied for fungal identification.Results Tinea capitis prevalence was high in the 1960s, with Trichophyton violaceum (41.9%) and Trichophyton schoenleinii (31.0%) being the most common pathogenic species, while the cases decreased sharply in the 1970s.Later in the 1990s, the proportion of Microsporum canis dropped to 1% after its peak (36.9%).T.violaceum had replaced T.schoenleinii and become the most common species (63%).T.schoenleinii and Trichophyton rubrum tended to infect adults, while T.violaceum, M.canis, Trichophyton interdigitale and Microsporum ferrugineum were more likely to infected children.The proportion of female patients among adults (64.6%) was higher than that of children (50.6%) (T.schoenleinii excluded) (P<0.05).Conclusion The pathogens of tinea capitis changed over time and now T.violaceum had become the most common species in the district.

Key words: tinea capitis, Trichophyton schoenleinii, Trichophyton violaceum, Microsporum canis, Trichophyton interdigitale

中图分类号:

R756.1

毛叶红, 何蒙文, 郑岳臣, 连昕, 曾敬思. 1960~2015年湖北及周边地区头癣病原菌变化情况分析[J]. 中国真菌学杂志, 2017, 12(2): 98-101,105.

MAO Ye-hong, HE Meng-wen, ZHENG Yue-chen, LIAN Xin, ZENG Jing-si. Causative agents of tinea capitis isolated from the patients in Hubei province and surrounding area in China during 1960-2015[J]. Chinese Journal of Mycology, 2017, 12(2): 98-101,105.

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