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中国真菌学杂志 2017, Vol. 12  Issue (2): 108-110,113.

病例报告 上一篇    下一篇

播散型毛霉病1例

宋敏1, 姜鲁宁2, 苏娜1, 蒋胜华2, 刘艳2   

  1. 1. 济宁医学院, 济宁 272067;
    2. 济宁医学院附属医院, 济宁 272029
  • 收稿日期:2016-11-05 出版日期:2017-04-28 发布日期:2017-04-28
  • 通讯作者: 姜鲁宁,E-mail:w13001786181@126.com E-mail:w13001786181@126.com
  • 作者简介:宋敏,女(汉族),硕士研究生在读.E-mail:1594084713@qq.com
  • 基金资助:

    济宁医学院附属医院“苗圃”科研计划项目(MP-2015-004)

A case report of disseminated mucormycosis

SONG Min1, JIANG Lu-ning2, SU Na1, JIANG Sheng-hua2, LIU Yan2   

  1. 1. Jining Medical College, Jining 272067;
    2. Affiliated Hospital of Jining Medical College, Jining 272029
  • Received:2016-11-05 Online:2017-04-28 Published:2017-04-28

摘要:

患者女,44岁,2015年1月16日以“咳嗽、咳痰、头痛伴发热10余天”收入院。胸部CT示双肺多发大小不等的圆形结节、空洞,边界清楚,其中最大空洞直径约1.8 cm,部分空洞内见软组织密度影。颅脑MRI平扫+增强示增强扫描:双额叶、左颞叶、左顶枕叶病灶及脑室内病灶呈环状、片状强化。行CT引导下肺穿刺,穿刺病理组织回示大部分为坏死性肉芽组织,其中见粗大无隔菌丝,符合毛霉菌感染,颅内病灶给予经验性抗毛霉菌治疗后好转,诊断为播散型毛霉病。

关键词: 毛霉菌病, 播散型, 肺,

Abstract:

A 44-year-old female patient was hospitalized with cough, expectoration, headache and fever over ten days;chest computed tomography (CT)examination showed multiple double-pulmonary circular nodules and cavities with different sizes and clear boundary.The maximum cavity diameter was about 1.8 cm, and the density of soft tissue was found in the part of the cavity.Head magnetic resonance imaging (MRI) combined with contrast-enha showed the bilateral frontal lobe, left temporal lobe, left parietal occipital lobe lesion and cerebral ventricle lesions were annular and patchy.CT-guided fine-needle percutaneous biopsy was performed.The biopsy showed many necrotic granulation tissue fungal hyphae was found.The case was diagnosed as DM.Intracranial lesions were improved after treatment with empirical anti mucormycosis treatment.

Key words: mucormycosis, disseminated, lung, brain

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