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中国真菌学杂志 2015, Vol. 10  Issue (1): 37-38.

病例报告 上一篇    下一篇

前交叉韧带重建术后黄曲霉感染1例

周万青1, 洪骏2, 张之烽1, 张葵1   

  1. 1. 南京大学医学院附属鼓楼医院检验科, 南京 210008;
    2. 南京军区南京总医院检验科, 南京 210002
  • 收稿日期:2014-05-30 出版日期:2015-02-28 发布日期:2015-02-28
  • 通讯作者: 张之烽,E-mail:njzhangzf@hotmail.com E-mail:njzhangzf@hotmail.com
  • 作者简介:周万青,男(汉族),硕士,主管技师.E-mail:zwq_096@163.com

A case of infection caused by Aspergillus flavus after anterior cruciate ligament reconstruction

ZHOU Wan-qing1, HONG Jun2, ZHANG Zhi-feng1, ZHANG Kui1   

  1. 1. Department of Laboratory Medicine, Nanjing Drum Tower Hospital, the affiliated Hospital of Nanjing University Medical School, Nanjing 210008;
    2. Department of Laboratory Medicine, Nanjing Jinling Hospital, the affiliated Hospital of Nanjing University Medical School, Nanjing 210002
  • Received:2014-05-30 Online:2015-02-28 Published:2015-02-28

摘要: 该文报道前交叉韧带重建术后感染黄曲霉1例.患者男,26岁.因陈旧性交叉韧带断裂在某医院行自体肌腱右膝前交叉韧带重建术.术后1周发生感染症状,常规抗细菌药物无效.根据病史、临床表现及真菌培养诊断为黄曲霉关节感染.经过关节腔内5%碳酸氢钠溶液冲洗并关节腔内两性霉素B灌注给药 (1%两性霉素B 20 mL,qd),联合伏立康唑 (200 mg,q12 h)口服抗真菌治疗,28 d后病情好转出院.

关键词: 黄曲霉, 前交叉韧带重建术, 感染

Abstract: This is a report of knee joint infection caused by Aspergillus flavus after anterior cruciate ligament reconstruction.A 26-year-old man was performed a surgery of cruciate ligament reconstruction with autologous tendon because of old cruciate ligament rupture.The symptoms of knee joint infection happened one week after the surgery and conventional anti-bacterial drugs showed ineffective.According to the history,clinical symptoms and the fungal culture positive with Aspergillus flavus,the patient was diagnosed as a fungal infection after surgery caused by Aspergillus flavus.After rinsing the joint cavity with 5% sodium bicarbonate solution and the use of amphotericin B (1% amphotericin B 20 mL,qd) infusion administration,combination use of voriconazole (200 mg,q12 h) oral for anti-fungal treatment,the patient's infection condition improved and was discharged after 28 days.

Key words: Aspergillus flavus, anterior cruciate ligament reconstruction, infection

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