皮肤癣菌分子生物学鉴定新进展

摘要/Abstract

摘要：

目前全球范围内皮肤癣菌感染率日渐升高，引起广泛关注。由于皮肤癣菌感染性疾病临床症状的非特异性，导致在临床工作中对于此类疾病的诊断和鉴别诊断遇到困难。为了能够准确地对皮肤癣菌病进行早期诊断，皮肤癣菌的鉴别就显得尤其重要。目前较为普及的鉴别方法主要有形态学方法和分子生物学方法。该文着重介绍发展较快的分子生物学方法，并比较其在皮肤癣菌病诊断和鉴别诊断中的灵敏度、特异性及准确率等。

关键词: 皮肤癣菌病, 皮肤癣菌, 鉴别诊断, 形态学方法, 分子生物学方法

Abstract:

Currently the infection of dermatophytes had increased worldwidely, and caused widespread concern. The non-specific clinical symptoms of dermatophytoses might result in difficulties in the diagnosis and differential diagnosis. In order to diagnose dermatophytoses accurately and early, identification of dermatophytes was especially important. Current methods of identification were mainly morphological and molecular biology methods. This article focused on the rapid development of molecular biological methods, and exhibited their sensitivity, specificity and accuracy in the diagnosis and differential diagnosis of dermatophytoses.

Key words: Dermatophytoses, Dermatophytes, differential diagnosis, morph-ological methods, molecular biological methods

中图分类号:

R379.2

刘昕, 马彦. 皮肤癣菌分子生物学鉴定新进展[J]. 中国真菌学杂志, 2014, 9(3): 186-188,192.

LIU Xin, MA Yan. Advance on molecular identification of Dermatophytes[J]. Chinese Journal of Mycology, 2014, 9(3): 186-188,192.

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