2007~2011年鄂州市气传致敏真菌调查及其与支气管哮喘的相关性

中国真菌学杂志　 2013, Vol. 8 　Issue (6): 358-360.

2007~2011年鄂州市气传致敏真菌调查及其与支气管哮喘的相关性

熊汉忠¹, 尹良琼², 付达东³, 张福瑜¹, 霍淑萍⁴, 王好艺⁵, 陈开琦⁶, 王志安¹

1. 鄂州市中心医院呼吸内科, 鄂州 436000;
2. 鄂州市中心医院检验科, 鄂州 436000;
3. 鄂州市中心医院ICU, 鄂州 436000;
4. 鄂州市中心医院眼科, 鄂州 436000;
5. 鄂州市中心医院药剂科; 鄂州 436000;
6. 鄂州市长港农场卫生院内科, 鄂州 436000

收稿日期:2013-09-18 出版日期:2013-12-28 发布日期:2013-12-28
通讯作者: 尹良琼，E-mail：415684970@qq.com E-mail:415684970@qq.com
作者简介:熊汉忠，男（汉族），硕士，副主任医师.E-mail：fhq000@126.com

A survey of airborne fungi and and correlation study with bronchial asthma from 2007 to 2011 in Ezhou

XIONG Han-zhong¹, YIN Liang-qiong², FU Da-dong³, ZHANG Fu-yu¹, HUO Shu-ping⁴, WANG Hao-yi⁵, CHEN Kai-qi⁶, WANG Zhi-an¹

1. Ezhou Central Hospital Respiratory Medicine, Ezhou 436000;
2. Ezhou Central Hospital Clinical Laboratory, Ezhou 436000;
3. Ezhou Central Hospital ICU, Ezhou 436000;
4. Ezhou Central Hospital Ophthalmology department, Ezhou 436000;
5. Ezhou Central Hospital Pharmacy Department, Ezhou 436000;
6. Department of medicine, Ezhou mayor Hong farm hospitals, Ezhou 436000

Received:2013-09-18 Online:2013-12-28 Published:2013-12-28

摘要/Abstract

摘要： 目的探讨2007年5月~2011年4月鄂州市气传致敏真菌和支气管哮喘关系，以了解该地区支气管哮喘情况。方法运用暴片调查法和暴皿调查法统计和记录鄂州市气传致敏真菌的种类及数量。选择该时期内鄂州市100例支气管哮喘患者采用真菌变应原浸液作过敏原皮试发现有35例患者皮内试验阳性，将35例发作期患者和40例稳定期支气管哮喘患者行曲霉特异性IgE测定。结果 100例支气管哮喘患者皮内实验组阳性35例，阳性率为35%，而在35例患者中IgE阳性有31例，检测符合率为88.58%，稳定期患者中阳性反应例数2例，阳性率为5%，两组阳性率比较差异具有显著性（P<0.05）。结论鄂州市气传致敏真菌和支气管哮喘密切相关，主要致病菌为曲霉，是支气管哮喘的致敏原之一，需要注意环境卫生以减少气传致敏真菌的数量。

关键词: 鄂州市, 气传致敏真菌, 支气管哮喘

Abstract: Objective To discuss the relationship betweenin airborne fungi and bronchial asthma from May 2007 to April 2011 in Ezhou,in order to understand the bronchial asthma in this area.Methods Using survey mathods of sheet glass and culture plate of exposure determination to count the species and quantity of airborne fungi in Ezhou. Fungi allergen skin test was performed on 100 cases which were diagnosed bronchial asthma and find out that 35 patients showed positive results on the intradermal skin test, Serum specific IgE was given to 35 patientsahd 40 healthy people.Results 35 cases showed positive result in 100 cases of bronchial asthma patients in Intradermal group, The positive rate was 35%,while 31 cases showed positive in specific IgE assay, coincidence of detection rate was 88.58%, there were 2 cases showed positive reaction in healthy people, the positive rate was 5%, The difference in positive rate between the two groups was significant (P<0.05).Conclusion airborne fungi is closely related to bronchial asthma, and it is one of sensitinogen to cause bronchial asthma. And also need to pay attention to environmental health to reduce the number of airborne fungi.

Key words: Ezhou, airborne fungi, Bronchial asthma

中图分类号:

R379

熊汉忠, 尹良琼, 付达东, 张福瑜, 霍淑萍, 王好艺, 陈开琦, 王志安. 2007~2011年鄂州市气传致敏真菌调查及其与支气管哮喘的相关性[J]. 中国真菌学杂志, 2013, 8(6): 358-360.

XIONG Han-zhong, YIN Liang-qiong, FU Da-dong, ZHANG Fu-yu, HUO Shu-ping, WANG Hao-yi, CHEN Kai-qi, WANG Zhi-an. A survey of airborne fungi and and correlation study with bronchial asthma from 2007 to 2011 in Ezhou[J]. Chinese Journal of Mycology, 2013, 8(6): 358-360.

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