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中国真菌学杂志 2013, Vol. 8  Issue (3): 179-184,191.

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医学真菌基因组学研究进展(上)

占萍, 王冲, 刘维达   

  1. 北京协和医学院, 中国医学科学院皮肤病研究所真菌科, 南京 210042
  • 收稿日期:2013-04-26 出版日期:2013-06-28 发布日期:2013-06-28
  • 通讯作者: 刘维达,E-mail:liumyco@hotmail.com E-mail:liumyco@hotmail.com
  • 作者简介:占萍,女 (汉族),博士,主治医师.E-mail:zhanping1980@163.com
  • 基金资助:
    国家973项目(2013CB531605)

The research advance of the medical fungal genomics

ZHAN ping, WANG Chong, LIU wei-da   

  1. Department of Mycology, Institute of Dermatology, Chinese Academy of Medical Science & Peking Union Medical College, Nanjing 210042, China
  • Received:2013-04-26 Online:2013-06-28 Published:2013-06-28

摘要: 近年来,一系列重要医学致病真菌全基因组数据陆续被公布,使人类对这些致病菌的认识提高到全新水平。本文在回溯医学真菌基因组学和基因组测序技术发展历程、综述其发展现状及应用的基础上,再分别介绍重要医学真菌全基因组测序的进展。

关键词: 真菌, 全基因组测序, 念珠菌, 隐球菌, 曲霉, 青霉, 皮肤癣菌, 接合菌

Abstract: A serial of medical fungus genome data have been published in recent years, by which human can make a better understanding of the pathogenesis of these pathogens. Here we try to review the history of the medical fungal genomics,genome sequencing technology and introduce the development and progress of clinical important medical fungi genome.

Key words: fungi, whole genome sequencing, Candida, Cryptococcus, Aspergillus, Penicillium, Dermatophytes, Zygomycetes

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