外阴阴道念珠菌病、复发性外阴阴道念珠菌病及健康人群甘露糖结合凝集素水平的分析研究

中国真菌学杂志　 2013, Vol. 8 　Issue (3): 160-162,168.

外阴阴道念珠菌病、复发性外阴阴道念珠菌病及健康人群甘露糖结合凝集素水平的分析研究

刘格, 王薇华, 孙静, 马雪枫, 陈爱群

深圳市宝安区妇幼保健院, 深圳 518000

收稿日期:2013-04-04 出版日期:2013-06-28 发布日期:2013-06-28
作者简介:刘格,女 (汉族),博士,主治医师.E-mail:coxzxll@163.com
基金资助:
深圳市宝安区科技局课题(2010703)

The study of the lectin level in healthy population,vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) groups

LIU Ge, WANG Wei-hua, SUN Jing, MA Xue-feng, CHEN ai-qun

Shenzhen Baoan Maternal And Child Health Hospital, Shenzhen 518000, China

Received:2013-04-04 Online:2013-06-28 Published:2013-06-28

摘要/Abstract

摘要： 目的观察健康人群、外阴阴道念珠菌病 (VVC)和复发性外阴阴道念珠菌病 (RVVC)的甘露糖结合凝集素水平。方法收集健康人群、VVC和RVVC病例,给予规范化治疗,观察治疗前、后各组MBL水平的变化,并进行随访。结果发现各组的MBL水平VVC组>RVVC组>健康组,但各组之间及各组本身治疗前后的MBL差异无显著性意义(P>0.05)。治疗后VVC组复发者5例,占14%,RVVC组复发者13例,达到48%,两组复发者与未复发者的MBL水平,经t检验无显著性差异(P>0.05)。结论 MBL的水平在VVC患者中的水平高于RVVC患者,两者的复发率基本与既往文献报道一致,对于VVC患者来说,MBL水平高于0.8 ng/mL似乎患RVVC的风险稍小些。

关键词: 外阴阴道念珠菌病, 甘露糖结合凝集素, 复发

Abstract: Objective To value the levels of mannose lectin in healthy population, vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) groups.Method All the VVC and RVVC cases were given standardized treatment. Compared with healthy population, the MBL levels before and after treatment were observed in these two groups.Results The MBL levels of vvc group,RVVC group,healthy group were arranged from high to low numerically. But there was no significant difference among groups or within every group before and after treatment(P>0.05). There were 14% (5/43) cases of recurrence in VVC group and 48% (13/30) cases of recurrence in RVVC group,respectively. There was no significant differecne of recurrence between VVC and RVVC groups(P>0.05).Conclusion The level of MBL is higher numerically in VVC group than the level in RVVC group. The recurrence in both groups is consistet with the previously literature. The VVC patients with MBL level higer than 0.8 ng/mL seems to have lower risk of suffering RVVC.

Key words: vulvovaginal candidiasis, mannan binding lectin, recurrence

中图分类号:

R756.2

刘格, 王薇华, 孙静, 马雪枫, 陈爱群. 外阴阴道念珠菌病、复发性外阴阴道念珠菌病及健康人群甘露糖结合凝集素水平的分析研究[J]. 中国真菌学杂志, 2013, 8(3): 160-162,168.

LIU Ge, WANG Wei-hua, SUN Jing, MA Xue-feng, CHEN ai-qun. The study of the lectin level in healthy population,vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC) groups[J]. Chinese Journal of Mycology, 2013, 8(3): 160-162,168.

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