欢迎访问《中国真菌学杂志》杂志官方网站,今天是 分享到:

中国真菌学杂志 2012, Vol. 7  Issue (6): 356-358,364.

病例报告 上一篇    下一篇

裴氏着色霉致着色芽生菌病1例并文献复习

刘芳1, 冯姣1, 孔庆涛1, 吴凡1, 任芳1, 沈永年2, 吕桂霞2, 桑红1   

  1. 1. 南京军区南京总医院皮肤科,南京 210002;
    2. 中国医学科学院协和医科大学皮肤病研究所,南京 210042
  • 收稿日期:2012-08-06 出版日期:2012-12-28 发布日期:2012-12-28
  • 通讯作者: 桑红 E-mail:shzwqzsl@163.com
  • 作者简介:刘芳,女 (汉族),硕士.E-mail:liufangndyx@hotmail.com

A case of Chromoblastomycosis caused by Fonsecaea pedrosoi and literature review

LIU Fang1, FENG Jiao1, KONG Qing-tao1, WU Fan1, REN Fang1, SHEN Yong-nian2, LV Gui-xia2, SANG Hong1   

  1. 1. Department of Dermatology,Nanjing General Hospital of Nanjing Military Command,Nanjing 210002,China;
    2. Institute of Dermatology,Chinese Academy of Medical Sciences,Peking Union Medical College,Nanjing 210042,China
  • Received:2012-08-06 Online:2012-12-28 Published:2012-12-28

摘要:

报道1例裴氏着色霉致左手背及腕部着色芽生菌病,通过文献复习统计并分析该病在我国的流行病学及临床特点。患者男,48岁,左手背部红斑、疣状增生伴瘙痒10 a。皮损组织病理检查示真皮中下层有炎细胞及多核巨细胞,PAS染色见硬壳小体。经真菌培养和分子鉴定为裴氏着色霉。经伊曲康唑600 mg每日口服,治疗3个月后好转。

关键词: 裴氏着色霉, 着色芽生菌病, 流行病学

Abstract:

Reported one case of left opisthenar and wrist chromoblastomycosis caused by Fonsecaea pedrosoi ,and statistical analysis the epidemiology and clinical characteristic in our country through literature retrieve. A 48-year-old man with infiltrated erythematous plaque,verrucous hyperplasia accompany with pruritus in left opisthenar and wrist for ten-years. Lesions Histopathology showed mixed inflammatory cell and multinucleated giant cells infiltrate with sclerotic bodies in the dermis. Positive periodic acid-schiff staining of sclerotic bodies. The isolate was identified as Fonsecaea pedrosoi by fungal examination, PCR and sequence analysis. The patient was treated with itraconazole 600mg daily for 3 months, with a complete resolution of the dermatosis.

Key words: Fonsecaea pedrosoi, Chromoblastomycosis, epidemiology

中图分类号: