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中国真菌学杂志 2012, Vol.  Issue (5): 287-289.

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637例甲真菌病临床类型及致病真菌分析

梁晓博1, 李廷慧1, 胡蓉1, 杨扬1, 吴建华2   

  1. 1. 解放军第309医院皮肤科, 北京 100091;
    2. 上海长海医院皮肤科, 上海 200433
  • 收稿日期:2011-07-20 出版日期:2012-10-28 发布日期:2012-10-28
  • 通讯作者: 吴建华,E-mail:wujh_ch@163.com E-mail:wujh_ch@163.com
  • 作者简介:梁晓博,男(汉族),博士,副主任医师.E-mail:liangxiaobo309@yahoo.cn

Clinical investigation and pathogenic fungus analysis of 637 onychomycosis cases

LIANG Xiao-bo1, LI Ting-hui1, HU Rong1, YANG Yang1, WU Jian-hua2   

  1. 1. Department of Dermatology, No.309 Hospital of PLA, Beijing 100091;
    2. Department of Dermatology, Changhai Hospital, Shanghai 200433
  • Received:2011-07-20 Online:2012-10-28 Published:2012-10-28

摘要: 目的 了解637例甲真菌病患者的临床分类、致病真菌菌种构成及其分布。方法 按甲真菌病诊断标准收集近3 a来637例真菌培养阳性甲真菌病患者并临床分类,按真菌学分类标准诊断致病菌种类,分析各菌种在临床病种、年龄段、性别等的分布。结果 临床分型以远端侧位甲下型为主 (72.06%)。菌种构成为皮肤癣菌占69.39%、酵母菌占18.68%、非皮肤癣菌霉菌占11.93%。皮肤癣菌中红色毛癣菌353株 (79.86% ),酵母菌中白念珠菌67株 (56.30%),非皮肤癣菌中以青霉和曲霉为主。致病菌种的分布在不同年龄段及性别间存在差异,但均以皮肤癣菌为主。结论 甲真菌病的临床类型以远端侧位甲下型为主, 红色毛癣菌为优势致病菌。

关键词: 甲真菌病, 致病菌, 皮肤癣菌, 酵母菌, 霉菌

Abstract: Objective To analyze the clinical features, pathogenic fungus distribution and correlation between fungus and clinical patterns of onychomycosis with positive fungal culture in 637 cases.Methods Fungal culture and clinical analysis were performed on 637 cases of onychomycosis with positive result by fungal cultivation.Results DLSO were the most frequently clinical patterns. Of all the 637 cases of onychomycosis with positive fungal culture. The rates of dermatophytes, yeasts and non-dermatophytic moulds were 69.39%,18.68% and 11.93% respectively. There are differences between patients with different sex and age. Dermatophytes were the dominate strains.Conclusion In Northwest Beijing region, the dominant clinical type of onychomycosis with positive fungal culture is DLSO. The most frequent pathogenic fungus of onychomycosis is Trichophyton spp.

Key words: onychomycosis, pathogen, dermatophyte, yeast, mould

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