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中国真菌学杂志 2012, Vol.  Issue (4): 228-229.

病例报告 上一篇    下一篇

1株多重耐药申克孢子丝菌感染的治疗

胡素泉1, 郭宁如1, 蔡晴1, 宋学东2, 李筱芳1, 吴绍熙1   

  1. 1. 中国医学科学院 北京协和医学院皮肤病研究所, 南京 210042;
    2. 安徽巢湖第一医院, 巢湖 238000
  • 收稿日期:2012-03-17 出版日期:2012-08-28 发布日期:2012-08-28
  • 通讯作者: 吴绍熙,E-mail:wushaoxi2001@yahoo.com.cn E-mail:wushaoxi2001@yahoo.com.cn
  • 作者简介:胡素泉,女(汉族),大学专科,主管技师.E-mail:shuquanhu@163.com

The treatment of multidrug-resistant Sporothrix schenckii infection:a case report

HU Su-quan1, GUO Ning-ru1, CAI Qing1, SONG Xue-dong2, LI Xiao-fang1, WU Shao-xi1   

  1. 1. Institute of Dermatology, Chinese Academy of Medical Sciences & PUMC, Nanjing 210042;
    2. First Hospital of Chaohu Anhui, Chaohu 238000
  • Received:2012-03-17 Online:2012-08-28 Published:2012-08-28

摘要: 报道1例由多重耐药申克孢子丝菌引起的面部孢子丝菌病。患者61岁男性,面部皮疹2 a余,先后口服伊曲康唑、特比萘芬和氟康唑治疗16个月无效。患者皮损经真菌镜检和培养确诊为孢子丝菌病,分离的申克孢子丝菌体外药敏试验显示其菌丝相和酵母相对上述三种药物均不敏感。给予患者口服10%碘化钾溶液治疗3个月获得痊愈。

关键词: 申克孢子丝菌, 孢子丝菌病, 多重耐药, 10%碘化钾

Abstract: A case of facial subcutaneous sporotrichsis caused by a multidrug-resistant Sporothrix schenckii strain was reported. A 61-year-old man had a history of facial plaques for 2 years. Whereas the patient had been treated with itraconazole, terbinafine and fluconazole successively for 16 months, the therapy was failed. According to mycological results of skin lesion, a diagnosis of sporotrichosis was made. However, the isolate of this case was not sensitive to itraconazole, terbinafine and fluconazole in both hyphae phase and yeast phase. The case had been cured by oral 10% potassium iodide for 3 months.

Key words: Sporothrix schenckii, sporotrichosis, multi-drug resistant, 10% potassium iodide

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