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中国真菌学杂志 2011, Vol. 6  Issue (1): 40-42.

病例报告 上一篇    下一篇

棕黑腐质霉(Humicola fuscoatra)导致真菌性腹膜炎1例

王澎, 谢秀丽, 王贺, 窦红涛, 孙宏莉, 王辉, 徐英春   

  1. 中国医学科学院北京协和医院检验科临床微生物专业组, 北京, 100730
  • 收稿日期:2010-08-05 出版日期:2011-02-28 发布日期:2011-02-28
  • 通讯作者: 徐英春,E-mail:xycpumch@yahoo.com.cn E-mail:xycpumch@yahoo.com.cn
  • 作者简介:王澎,女(汉族),学士,主管技师.E-mail:PUMCH2005@126.com

A case of fungal peritonitis caused by Humicola fuscoatra

WANG Peng, XIE Xiu-li, WANG He, DOU Hong-tao, SUN Hong-li, WANG Hui, XU Ying-Chun   

  1. Department of Clinical Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
  • Received:2010-08-05 Online:2011-02-28 Published:2011-02-28

摘要: 报道1例由棕黑腐质霉属(Humicola fuscoatra)导致的真菌性腹膜炎。此菌分离自1名长期腹膜透析患者的腹水。腐质霉属在自然界广泛存在,棕黑腐质霉导致的人类感染罕见。现对棕黑腐质霉的真菌学特点进行研究,并进行分子测序。体外药物敏感性试验结果对伊曲康唑的MIC为0.008μg/mL,伏立康唑的MIC为0.016μg/mL,两性霉素B的MIC为1.5μg/mL。患者拔除腹透管,改行血液透析。口服伊曲康唑0.1 g/12 h,28 d后病情明显改善,出院。

关键词: 棕黑腐质霉, 真菌性腹膜炎, 真菌感染

Abstract: A case of fungal peritonitis in CAPD patient caused by Humicola fuscoatra was reported.Characteristic of the pathogen,which widely spreads in the nature but rare in human infection was described and molecule examination was carefully performed.MICs of itraconazole,voriconazole and amphotericin B were 0.008 μg/mL,0.016 μg/mL and 1.5 μg/mL,respectively.The patient showed improved condition and was discharged from the hospital by oral itroconazole(0.1 g,q12 h) and hemodialysis.

Key words: Humicola fuscoatra, fungal peritonitis, fungal infection

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